Drink Less With Naltrexone

Naltexone is a medication that has been used to help people reduce the how much alcohol they drink. It’s typically used to help people change their drinking habits and is taken 30 minutes before drinking. Naltrexone is a well studied drug to use for reduction of alcohol consumption, appearing in 30+ studies over the past 2 decades. It can be effective as a daily use medication or taken as needed. Success rates can be increased when combined with behavioral health therapy.


Treatment Benefits


Clinically tested and FDA cleared


No fatal side effects or severe allergic reactions


Prescribed by US licensed physicians


Legally sent to you from a licensed pharmacy


The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.

Naltrexone was originally developed to help treat opioid addiction, but researchers found it also to be effective in reducing people’s desire to consume alcoholic drinks. If you’ve had pleasurable experiences drinking alcohol in the past, your brain can associate those pleasurable experiences with the presence of alcohol. If you drink alcohol regularly, then your body will produce endorphins when you drink to indicate that pleasurable experiences may follow. These endorphins are actually endogenous opiates (a scientific way of saying opioids created by your body).

The release of these endorphins for many people translates into a desire to keep drinking. Unfortunately this endorphin system is not very sophisticated and can’t tell if you have a big meeting tomorrow or an important test coming up that week. As a result, it can feel good just to keep drinking regardless if there are any obvious negative consequences.

Naltrexone blocks the receptor of these endogenous opiates and removes the pleasurable feeling just drinking brings. You’ll still feel the effects of alcohol, but you won’t experience the desire to keep drinking, just to keep drinking. For many people this translates into less drinks overall, especially the last drinks of a day or evening, which in many cases are the least valuable and the most costly for productivity the next day.

Naltrexone has been shown to be effective by many studies, but it’s not a magic pill. While it can be very effective in reducing the craving or desire to drink or keep drinking, it doesn’t necessarily address underlying reasons for drinking heavily on a regular basis. If you feel like you’re unable to control your drinking, it can also be helpful to speak to one of our clinical staff. They leverage person centered care, meaning they’ll help you reach your goals no matter what they are and will never pressure you to quit drinking altogether.

Naltrexone has been approved for treating opioid dependency since the 1980s and was approved by the FDA as a treatment to reduce alcohol use in 1995.

Why Naltrexone

While Naltrexone isn’t the only medication that you can leverage to help you reduce your drinking, but it has a track record of success and a proven safety profile. When you have your online consultation with one of our providers.


Naltrexone has been studied to help reduce alcohol consumption in 30+ clinical trials over a 20 year period and has consistently shown positive results, especially in reducing amount of drinking.

Proven Safety Profile

Naltrexone has been prescribed for over 30 years and has been effective for a wide range of people. It has no fatal side effects or severe allergic reactions.


You can use Naltrexone as needed to reduce your drinking. Naltrexone is also safe for use by people with or without other conditions such as hypertension, type 2 diabetes, or dyslipidemia.

What is Naltrexone?

Naltrexone is a drug used to treat opioid use disorder or alcohol use disorder. It comes in a pill form or as a long acting injectable. Naltrexone can be taken as needed in any form, but people typically use the pill form for as needed doses. The dosage for Naltrexone is usually based on your medical condition and response to the medication and treatment. 

Confidant prescribes medications following online consultations. These prescriptions are fulfilled by a licensed pharmacy and all medications are genuine as a result. Naltrexone is FDA-approved to treat opioid use disorder (OUD) and alcohol use disorder (AUD). The medication can be taken as needed or daily to treat OUD or AUD.

Do not take Naltrexone if you:

  • Have alcoholic hepatitis, as the medication can make this condition worse

  • Are taking opioid pain medications to manage a chronic condition or chronic pain. Opioid pain medications will be blocked by Naltrexone, making them ineffective. You can also enter precipitated withdrawal if you’re taking larger doses of opioids.

To make sure Naltrexone is right for you, you should disclose all important medical information to your Confidant provider. Initial prescription, as well as adjustments to dosage should be monitored for side effects and potential effects on pre-existing conditions.

Before taking naltrexone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current or recent use (in the last 7 to 14 days) of any type of opioid drug (such as morphine, methadone, buprenorphine), kidney disease, liver disease.

You should carry or wear medical identification stating that you are taking this drug so that appropriate treatment can be given in a medical emergency.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). After stopping naltrexone treatment, you may be more sensitive to lower doses of opioids, increasing your risk of possibly life-threatening side effects from the opioid (e.g., decreased breathing, loss of consciousness).

This medication blocks the effects of opiate drugs (including heroin) and similar drugs (opioids). However, large doses of heroin or opioids can overcome this block. Trying to overcome this block is very dangerous and may cause serious injury, loss of consciousness, and death. Make sure you completely understand and accept the risks and benefits of using this medication. Follow your doctor's instructions closely.

Before having surgery or any medical treatment, tell your doctor or dentist that you are taking this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.

Nausea, headache, dizziness, anxiety, tiredness, and trouble sleeping may occur. In a small number of people, mild opiate withdrawal symptoms may occur, including abdominal cramps, restlessness, bone/joint pain, muscle aches, and runny nose. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sudden opiate withdrawal symptoms can occur within minutes after taking naltrexone. Tell your doctor right away if any of these withdrawal symptoms occur: abdominal cramps, nausea/vomiting, diarrhea, joint/bone/muscle aches, mental/mood changes (e.g., anxiety, confusion, extreme sleepiness, visual hallucinations), runny nose.

Naltrexone has rarely caused serious liver disease. The risk is increased when larger doses are used. Discuss the risks and benefits with your doctor. Stop using this medication and tell your doctor right away if you develop symptoms of liver disease, including: persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Common and Rare Side EffectsAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

    • Skin rash


    • Abdominal or stomach pain (severe)

    • blurred vision, aching, burning, or swollen eyes

    • chest pain

    • confusion

    • discomfort while urinating or frequent urination

    • fever

    • hallucinations or seeing, hearing, or feeling things that are not there

    • itching

    • mental depression or other mood or mental changes

    • ringing or buzzing in the ears

    • shortness of breath

    • swelling of the face, feet, or lower legs

    • weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

    • abdominal or stomach cramping or pain (mild or moderate)

    • anxiety, nervousness, restlessness or trouble sleeping

    • headache

    • joint or muscle pain

    • nausea or vomiting

    • unusual tiredness

Less common

    • chills

    • constipation

    • cough, hoarseness, runny or stuffy nose, sinus problems, sneezing, or sore throat

    • diarrhea

    • dizziness

    • fast or pounding heartbeat

    • increased thirst

    • irritability

    • loss of appetite

    • sexual problems in males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Alfentanil

  • Alphaprodine

  • Anileridine

  • Benzhydrocodone

  • Buprenorphine

  • Butorphanol

  • Codeine

  • Diacetylmorphine

  • Difenoxin

  • Dihydrocodeine

  • Diphenoxylate

  • Ethylmorphine

  • Fentanyl

  • Hydrocodone

  • Hydromorphone

  • Ketobemidone

  • Levorphanol

  • Meperidine

  • Methadone

  • Morphine

  • Morphine Sulfate Liposome

  • Nalbuphine

  • Nicomorphine

  • Opium

  • Opium Alkaloids

  • Oxycodone

  • Oxymorphone

  • Papaveretum

  • Paregoric

  • Piritramide

  • Propoxyphene

  • Remifentanil

  • Sufentanil

  • Tapentadol

  • Tilidine

  • Tramadol

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Bremelanotide

  • Naldemedine

  • Naloxegol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Lofexidine

  • Yohimbine