Learning library
Buprenorphine Suboxone and Subutex
Mixing Suboxone and Kratom: Risks and Precautions

Mixing Suboxone and Kratom: Risks and Precautions

There is talk of kratom and Suboxone being used together to treat opioid withdrawal, but mixing the two can actually make withdrawal worse.

Suboxone is used to treat opioid addiction, and it works because it contains a combination of buprenorphine and naloxone. Buprenorphine acts as a partial opioid agonist, meaning that it acts similarly to other opioid drugs and can reduce cravings and withdrawal symptoms. Naloxone increases the benefits of Suboxone by discouraging people from misusing the medication. While Suboxone is used to treat addiction to opioid drugs like heroin or oxycodone, some people may think they can use this medication to treat addiction to kratom. Others may believe that it is safe to mix kratom and Suboxone. Below, learn all about Suboxone and kratom, including whether it is safe to combine these two substances. 

What Is Suboxone?

Suboxone is a prescription drug used in medication-assisted treatment for opioid use disorder. It contains a combination of buprenorphine and naloxone, and it helps people to stay engaged in addiction treatment by reducing cravings and withdrawal side effects. Ideally, people also participate in counseling while taking Suboxone. 

Suboxone comes in a film that is dissolved either under the tongue or between the cheek and gums. Treatment with Suboxone begins with an induction phase, during which a doctor stabilizes patients on a suitable dose of the medication. This phase lasts for about a week, and a doctor may prescribe other medications that also treat withdrawal symptoms.

After the induction phase, a patient moves toward maintenance treatment. They will take Suboxone every day, sometimes for months or even years, to help them stay in recovery. 

What Is Kratom?

Kratom comes from a tree that grows in Southeast Asia, and people may misuse its leaves or derivatives in order to relax or feel “high.” Interestingly, the drug has both stimulant and opioid-like effects. The stimulant effects of kratom result in increased energy, feelings of alertness, and rapid heart rate, whereas the opioid effects can relieve pain and create a feeling of relaxation. 

People use kratom by swallowing capsules or powders that contain plant matter, or by taking a liquid extract, brewing leaves into tea, or mixing kratom powder with food or drinks. 

In Southeast Asia, kratom has been used for hundreds of years as a medicinal plant, but it can come with negative side effects, which vary in severity depending upon how strong of a dose of kratom a person takes. For instance, some people have only mild side effects, such as nausea, constipation, dizziness, and feelings of drowsiness. Others may have more severe reactions, including high blood pressure, seizures, tremors, confusion, and slowed breathing.

 

How Does Kratom Work For Opioid Withdrawals?

People who are interested in kratom and Suboxone may ask, “Does kratom help with withdrawal?” since kratom produces opioid-like effects. According to scientists, kratom does act as a partial opioid agonist, and its effects are similar to morphine. This is because kratom contains two compounds, mitragynine and 7-hydroxymitragynine, which have opioid-like effects. In fact, 7-hydroxymitragynine is believed to be even stronger than morphine. 

Since kratom has opioid effects, people may take kratom to manage withdrawal symptoms. Theoretically, kratom could work for opioid withdrawal because of its chemical properties, and people may use it for this purpose, but it is not approved as a medication.

 

Kratom vs. Suboxone 

Kratom and Suboxone both activate the brain’s opioid receptors, but there are differences between Suboxone and kratom. 

Different Activation Of Opioid Receptors

Kratom activates mu- and delta- opioid receptors in the brain, whereas buprenorphine, the active ingredient in Suboxone, activates  mu-opioid receptors, but only partially. This feature is what makes buprenorphine so unique. 

FDA Approval 

Another difference between Suboxone and kratom is that Suboxone is FDA-approved for treating opioid addiction, whereas kratom is not. This means that the government has not tested the safety of kratom, and it is not a regulated medication. 

Strength And Misuse Potential

Kratom is stronger than Suboxone, because it does not have a ceiling effect like Suboxone does. In addition, unlike Suboxone, kratom does not contain naloxone to discourage misuse of the drug. People may be more likely to misuse kratom, making it a riskier drug. 

Kratom Withdrawal Symptoms

Since kratom has opioid effects, it can be addictive, just like other opioid drugs. This means that when a person stops taking kratom, they can experience uncomfortable withdrawal side effects, including:

  • Anxiety
  • Anger
  • Sadness
  • Diarrhea
  • Reduced appetite
  • Fever
  • Hot flashes
  • Muscle spasms
  • Pain
  • Sleep problems
  • Runny nose 

Coming off kratom after an extended period of use can be uncomfortable, and patients benefit from seeking addiction treatment to help them manage withdrawal symptoms. 

Can You Take Kratom With Suboxone? 

It is not recommended to take kratom with Suboxone, because of the effects of the latter. Suboxone is intended to be a partial opioid agonist, and it binds very strongly to the mu opioid receptors, meaning that it will block the effects of other opioids. When you take kratom and Suboxone together, the Suboxone can send you into opioid withdrawal, which can be extremely unpleasant. 

How Long Must I Wait To Take Suboxone After Taking Kratom?

Taking Suboxone after kratom can send you into opioid withdrawal, especially if you are dependent upon kratom. If you have a kratom dependence, or if you are beginning opioid addiction treatment with Suboxone, you should wait until you begin to experience opioid withdrawal symptoms before you take a dose of Suboxone. 

If you have questions about your specific situation, it is important to consult with a Suboxone doctor, and tell your doctor about any other substances, including kratom, that you have been using. 

What Happens If You Combine Kratom And Suboxone?

Since kratom has opioid effects and is known to be an opioid receptor agonist, taking kratom with Suboxone will likely result in strong withdrawal effects. You should not take Suboxone immediately after taking kratom. 

How To Use Kratom To Get Off Suboxone

Using kratom to get off Suboxone is not recommended. Kratom is not an approved medication for any uses, let alone opioid withdrawal and addiction. If you’re taking Suboxone and would like to discontinue your use of the medication, it is important to discuss this with your doctor, who can help you develop a Suboxone tapering regimen.

🗓️
Book with Confidant

Book with a vetted Confidant Health provider

Book appointment

Other FAQs About Kratom And Suboxone

The following information is also helpful if you have questions about taking kratom and Suboxone together. 

Can You Quit Kratom With Suboxone?

Suboxone is approved for treatment of opioid addiction. Kratom is known to have opioid effects, and kratom addiction may improve with methods traditionally used in opioid addiction treatment. Always consult with a doctor if you have questions about treating kratom addiction. 

What Would Happen If You Take Kratom While Being Prescribed Suboxone?

Taking Suboxone and kratom together is likely to send you into kratom precipitated withdrawal, because Suboxone blocks the effects of opioid drugs. Kratom is known to have opioid effects and should not be taken with prescription Suboxone. 

Is It Safe To Use Kratom For Suboxone Withdrawal?

Kratom is not an approved medication; therefore, its safety and effectiveness has not been tested. Kratom for suboxone detox is not recommended, and you should always consult with a doctor before discontinuing Suboxone or trying to manage Suboxone withdrawal. 

Consult With An Online Suboxone Doctor At Confidant 

If you’re looking for opioid addiction treatment, Confidant offers an online Suboxone clinic that can be accessed from anywhere. Simply download the Confidant app on the Apple Store or Google Play Store to begin working with an online Suboxone doctor today. 

This article has been medically reviewed by
Erin Hillers
Erin Hillers
Erin Hillers
Nurse Practitioner

Erin is a Nurse Practitioner with 8 years of experience in midwifery and women's health. She has spent the past 5 years specializing in the treatment of opioid and alcohol use disorders.

Book appointment
👍
Recommended reading
4 mins
read time
Getting Emergency Suboxone: 3 Ways To Obtain It Quickly
4 mins
read time
Suboxone Telemedicine: How it Works and Benefits
4 mins
read time
How to Find Medicaid-Accepting Suboxone Doctors Near You
4 mins
read time
4 Common Ways to Administer Naloxone
4 mins
read time
A Comprehensive Guide to Suboxone Use & Pregnancy
4 mins
read time
Comprehensive Guide to Subutex vs. Suboxone
4 mins
read time
Guide to Different Suboxone Pills
4 mins
read time
Sublocade vs Suboxone: Choosing the Right Option
4 mins
read time
Suboxone Sublingual Film: A Quick Guide
4 mins
read time
Alvogen's Suboxone: Frequently Asked Questions
4 mins
read time
Belbuca vs Suboxone: Comparing the Two
4 mins
read time
Buprenorphine and How It Works
4 mins
read time
Can Nurse Practitioners Prescribe Buprenorphine?
4 mins
read time
Buprenorphine as a Painkiller: What You Need to Know
4 mins
read time
Can Psychiatrists Prescribe Suboxone?
4 mins
read time
Can Nurse Practitioners Prescribe Buprenorphine for Pain?
4 mins
read time
Can Suboxone be Called into a Pharmacy?
4 mins
read time
Can Suboxone be Used to Treat Pain?
4 mins
read time
Suboxone Doctors and Prescribing Benzodiazepines
4 mins
read time
Can Suboxone Lead to Addiction? Understanding the Risks
4 mins
read time
Can Taking Suboxone Affect Breastfeeding?
4 mins
read time
Can You Overdose on Suboxone?
4 mins
read time
Is It Possible to Shoot Suboxone?
4 mins
read time
Is It Possible to Smoke Suboxone?
4 mins
read time
Can You Take Ibuprofen with Buprenorphine?
4 mins
read time
Can You Take Methadone with Buprenorphine?
4 mins
read time
Can You Take Seroquel and Suboxone Together?
4 mins
read time
Can You Take Tramadol with Suboxone?
4 mins
read time
Can You Take Xanax with Suboxone?
4 mins
read time
A Guide to Suboxone Prescriptions
4 mins
read time
Dealing with Suboxone Withdrawal: Symptoms and Remedies
4 mins
read time
Do Employers Test for Buprenorphine?
4 mins
read time
If Suboxone Dissolves, Can you Swallow it?
4 mins
read time
Does Suboxone Block Methadone?
4 mins
read time
Does buprenorphine show up as an opiate?
4 mins
read time
Suboxone and Constipation: Understanding the Link
4 mins
read time
Suboxone and Weight Gain: Is There a Connection?
4 mins
read time
Does Suboxone Cause a High?
4 mins
read time
Suboxone and Sleepiness: What You Need to Know
4 mins
read time
Gabapentin & Suboxone: Can You Take Them Together?
4 mins
read time
Generic Suboxone: Uses, Forms and More
4 mins
read time
How and Where to Purchase Suboxone Online
4 mins
read time
How does buprenorphine actually work?
4 mins
read time
How does Suboxone affect your mood?
4 mins
read time
How is buprenorphine taken?
4 mins
read time
How Long Does It Take for Suboxone to Kick In?
4 mins
read time
How Long Does Suboxone Block Opiates?
5 mins
read time
How Long Does Suboxone Stay in Your System?
4 mins
read time
How long should you be on Suboxone?
4 mins
read time
How Long Should You Be Taking Suboxone For?
4 mins
read time
How the Suboxone Spit Method Works
4 mins
read time
Getting Suboxone: A Quick Guide
4 mins
read time
How to Maximize Suboxone Absorption
4 mins
read time
How To Successfully Taper Off Suboxone
4 mins
read time
Is Belbuca the same as Suboxone?
4 mins
read time
Is Buprenorphine a Stimulant?
4 mins
read time
Is Buprenorphine an Opiate?
4 mins
read time
Effectiveness of Buprenorphine for Chronic Pain
4 mins
read time
FDA Approval of Buprenorphine for Pain Management
4 mins
read time
Buprenorphine vs Suboxone: Understanding the Distinction
4 mins
read time
Buprenorphine for Depression: Is it FDA Approved?
4 mins
read time
Combining Klonopin or Lorazepam with Suboxone: Is It Safe?
4 mins
read time
Mixing Suboxone and Kratom: Risks and Precautions
4 mins
read time
Liver Safety and Suboxone Use: What You Need to Know
4 mins
read time
Long-term Use of Suboxone: Risks and Benefits
4 mins
read time
Methadone vs Buprenorphine: Similarities and Differences
4 mins
read time
Methadone vs Suboxone: Comparison and Contrast
4 mins
read time
Managing Sexual Side Effects of Suboxone
4 mins
read time
Online Suboxone Doctors and Their Role
4 mins
read time
Treatment Outcomes with Buprenorphine: What to Expect
4 mins
read time
Quick Guide to Getting Generic Suboxone
4 mins
read time
Possible Side Effects of Buprenorphine Use
4 mins
read time
Signs that Your Suboxone Dose May Need Adjusting
4 mins
read time
Patient Education for Suboxone (Buprenorphine/Naloxone)
4 mins
read time
Suboxone Dosage: A Guide to Safe and Effective Use
4 mins
read time
Suboxone Doses: A Chart for Easy Reference
4 mins
read time
Suboxone Ingredients: A Comprehensive Guide
4 mins
read time
Suboxone vs. Vivitrol: Uses, Forms, and More
4 mins
read time
The Beginner's Guide to Suboxone Laws
4 mins
read time
Withdrawal Symptoms of Suboxone: What to Expect
4 mins
read time
What Do Generic Suboxone Strips Look Like?
4 mins
read time
Identifying Each Form of Suboxone
4 mins
read time
What Happens When Suboxone and Alcohol Mix?
4 mins
read time
Swallowing Suboxone: What to Know
4 mins
read time
Daily Maximum Dosage of Suboxone: What You Need to Know
4 mins
read time
Suboxone and Medications: What Not to Take Together
4 mins
read time
What Schedule Drug is Suboxone Classified As? Understanding the Regulations
4 mins
read time
Buprenorphine Schedule and Regulations
4 mins
read time
What to Consider When Choosing a Suboxone Doctor
4 mins
read time
What to Know About Suboxone Shots
4 mins
read time
When Can You Take Subutex?
4 mins
read time
When to Take Suboxone: A Complete Guide
4 mins
read time
Where to Get Coupons for Suboxone
4 mins
read time
Where Can I Find Suboxone Treatment Centers Near Me?
4 mins
read time
Suboxone's Receptor Targets: A Comprehensive Overview
4 mins
read time
White Suboxone Pill: A Complete Guide
4 mins
read time
Why is Naloxone Added to Buprenorphine?
4 mins
read time
Why is Buprenorphine Not Widely Available?
4 mins
read time
Zubsolv vs. Suboxone: A Brief Comparison Guide
Confidant mobile app screens
Get immediate access to the care you need today

Scan the QR code below to download the app.

QR code to download the app
Download on the App StoreGet it on Google Play